TYRA · Insider trading · 13F holders · Congress trades
Tyra Biosciences, Inc. (TYRA)
Who is buying and selling TYRA: company insiders on SEC Form 4, hedge funds and superinvestors on Form 13F, and members of Congress under the STOCK Act. Every figure links to the filing or page it comes from.
- 13F filers holding
- 17
- Insider buys, 90 days
- $20K
- Insider sales, 90 days
- $0
- Congress trades, 12 months
- 0
TYRA at a glance
- Between Aug 1, 2026 and Oct 29, 2026, 1 TYRA insider filed 1 open-market purchase worth $20K on SEC Form 4.
- 17 13F filers hold TYRA among their 50 largest positions, worth $929.0M combined, including Peter Kolchinsky and James Flynn. The biggest bets by portfolio weight are 5AM Venture Management, LLC (11.4%), Nextech Invest Ltd. (5.4%) and Sio Capital Management, LLC (3.8%). In their latest 13Fs, 1 manager opened a new position and 3 added to one.
- No member of Congress has disclosed a trade in TYRA.
- TYRA last closed at $21.48 on Oct 29, 2026.
TYRA insider trading
Between Aug 1, 2026 and Oct 29, 2026, 1 TYRA insider filed 1 open-market purchase worth $20K on SEC Form 4.
| Filed | Insider | Role | Trade | Shares | Price | Value | Form 4 |
|---|---|---|---|---|---|---|---|
| Sep 11, 2026 | Verjee Rehan | Director | Buy | 971.894 | $20.58 | $20K | SEC |
Who owns TYRA? Hedge funds and superinvestors
17 13F filers hold TYRA among their 50 largest positions, worth $929.0M combined, including Peter Kolchinsky and James Flynn. The biggest bets by portfolio weight are 5AM Venture Management, LLC (11.4%), Nextech Invest Ltd. (5.4%) and Sio Capital Management, LLC (3.8%). In their latest 13Fs, 1 manager opened a new position and 3 added to one.
Superinvestors holding TYRA: Peter Kolchinsky 3.4% · James Flynn 0.4%
| Manager | % of portfolio | Value | Shares | Last quarter | 13F |
|---|---|---|---|---|---|
| Peter KolchinskyHedge fund | 3.4% | $389.6M | 12,198,625 | +0.0% shares | Q2 2026 |
| Nextech Invest Ltd.Hedge fund | 5.4% | $113.5M | 3,553,585 | -12.4% shares | Q2 2026 |
| TCG Crossover Management, LLCHedge fund | 2.5% | $103.8M | 3,248,980 | +0.0% shares | Q2 2026 |
| Commodore Capital LPHedge fund | 3.6% | $59.9M | 1,875,000 | -24.2% shares | Q2 2026 |
| Paradigm Biocapital Advisors LPHedge fund | 1.1% | $58.4M | 1,828,607 | -11.0% shares | Q2 2026 |
| Bvf Inc/ilInvestment manager | 1.2% | $47.1M | 1,476,196 | -25.3% shares | Q2 2026 |
| 5AM Venture Management, LLCVenture capital | 11.4% | $32.9M | 1,029,298 | +0.0% shares | Q2 2026 |
| James FlynnHedge fund | 0.4% | $32.5M | 1,017,000 | — | Q2 2026 |
| Caligan Partners LPHedge fund | 1.2% | $25.8M | 806,986 | -36.8% shares | Q2 2026 |
| Sio Capital Management, LLCHedge fund | 3.8% | $22.2M | 695,315 | +14.8% shares | Q2 2026 |
| Stempoint Capital LPHedge fund | 3.5% | $20.2M | 632,754 | +227.6% shares | Q2 2026 |
| Defilade Capital Management, L.P.Hedge fund | 1.6% | $12.0M | 376,870 | New | Q2 2026 |
| HighVista Strategies LLCHedge fund | 1.3% | $5.9M | 184,774 | +40.7% shares | Q2 2026 |
| Kalehua Capital Management LLCHedge fund | 1.7% | $2.4M | 74,465 | +0.0% shares | Q2 2026 |
| Verdad Advisers, LPAsset manager | 1.1% | $1.1M | 36,003 | — | Q2 2026 |
| Sofinnova Investments, Inc.Hedge fund | 0.1% | $1.0M | 32,267 | -84.2% shares | Q2 2026 |
| Elmind Capital, LPHedge fund | 0.2% | $639K | 20,000 | -94.3% shares | Q2 2026 |
Each manager counts with its latest 13F (Q2 2026: 17). Screen TYRA in the grand portfolio →
TYRA stock trades by members of Congress
No member of Congress has disclosed a trade in TYRA.
TYRA questions and answers
Are insiders buying TYRA stock?
Between Aug 1, 2026 and Oct 29, 2026, 1 TYRA insider filed 1 open-market purchase worth $20K on SEC Form 4.
Which hedge funds own TYRA?
17 13F filers hold TYRA among their 50 largest positions, worth $929.0M combined, including Peter Kolchinsky and James Flynn. The biggest bets by portfolio weight are 5AM Venture Management, LLC (11.4%), Nextech Invest Ltd. (5.4%) and Sio Capital Management, LLC (3.8%). In their latest 13Fs, 1 manager opened a new position and 3 added to one.
Has Congress traded TYRA?
No member of Congress has disclosed a trade in TYRA.
Who is the largest holder of TYRA?
Among 13F filers, Peter Kolchinsky reports the largest TYRA position, $389.6M (12,198,625 shares) in its Q2 2026 13F. The biggest bet by portfolio weight is 5AM Venture Management, LLC's: 11.4% of its portfolio.
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