KPTI · Insider trading · 13F holders · Congress trades
Karyopharm Therapeutics Inc. (KPTI)
Who is buying and selling KPTI: company insiders on SEC Form 4, hedge funds and superinvestors on Form 13F, and members of Congress under the STOCK Act. Every figure links to the filing or page it comes from.
- 13F filers holding
- 7
- Insider buys, 90 days
- $0
- Insider sales, 90 days
- $2K
- Congress trades, 12 months
- 1
KPTI at a glance
- Between Aug 1, 2026 and Oct 29, 2026, 1 KPTI insider filed 3 sales worth $2K on SEC Form 4, and no open-market purchases.
- 7 13F filers hold KPTI among their 50 largest positions, worth $45.9M combined. The biggest bets by portfolio weight are Kalehua Capital Management LLC (4.8%), Acorn Capital Advisors, LLC (4.0%) and Catalio Capital Management, LP (1.7%). In their latest 13Fs, 2 managers opened a new position and 3 added to one.
- Members of Congress have disclosed 1 KPTI trade since 2025, 0 purchases and 1 sale in the past year; the latest was Ashley Moody (R-FL), selling $1K–15K on Feb 20, 2025.
- KPTI last closed at $0.88 on Oct 29, 2026.
KPTI insider trading
Between Aug 1, 2026 and Oct 29, 2026, 1 KPTI insider filed 3 sales worth $2K on SEC Form 4, and no open-market purchases.
| Filed | Insider | Role | Trade | Shares | Price | Value | Form 4 |
|---|---|---|---|---|---|---|---|
| Oct 19, 2026 | Abate Kristin | Chief Accounting Officer | Sale | 4,788 | $0.34 | $2K | SEC |
| Oct 2, 2026 | Abate Kristin | Chief Accounting Officer | Sale | 378 | $1.19 | $449.82 | SEC |
| Sep 2, 2026 | Abate Kristin | Chief Accounting Officer | Sale | 19 | $2.02 | $38.38 | SEC |
Who owns KPTI? Hedge funds and superinvestors
7 13F filers hold KPTI among their 50 largest positions, worth $45.9M combined. The biggest bets by portfolio weight are Kalehua Capital Management LLC (4.8%), Acorn Capital Advisors, LLC (4.0%) and Catalio Capital Management, LP (1.7%). In their latest 13Fs, 2 managers opened a new position and 3 added to one.
| Manager | % of portfolio | Value | Shares | Last quarter | 13F |
|---|---|---|---|---|---|
| Acorn Capital Advisors, LLCHedge fund | 4.0% | $14.8M | 1,518,113 | +427.4% shares | Q2 2026 |
| Catalio Capital Management, LPHedge fund | 1.7% | $9.2M | 940,855 | +4.8% shares | Q2 2026 |
| Avidity Partners Management LPHedge fund | 1.4% | $9.0M | 924,487 | +99.4% shares | Q2 2026 |
| Kalehua Capital Management LLCHedge fund | 4.8% | $6.7M | 685,644 | New | Q2 2026 |
| NEA Management Company, LLCHedge fund | 0.4% | $5.6M | 576,780 | New | Q2 2026 |
| Silverback Asset Management LLCInstitutional asset manager | 1.1% | $293K | 30,000 | -53.8% shares | Q2 2026 |
| Velan Capital Investment Management LPHedge fund | 0.1% | $195K | 20,000 | +33.3% shares | Q2 2026 |
Each manager counts with its latest 13F (Q2 2026: 7). Screen KPTI in the grand portfolio →
KPTI stock trades by members of Congress
Members of Congress have disclosed 1 KPTI trade since 2025, 0 purchases and 1 sale in the past year; the latest was Ashley Moody (R-FL), selling $1K–15K on Feb 20, 2025.
| Filed | Member | Trade | Amount | Traded | Since |
|---|---|---|---|---|---|
| Mar 22, 2025 | Ashley MoodyR-FL · Senate | Sale | $1K–15K | Feb 20, 2025 | -92.3% |
KPTI questions and answers
Are insiders buying KPTI stock?
Between Aug 1, 2026 and Oct 29, 2026, 1 KPTI insider filed 3 sales worth $2K on SEC Form 4, and no open-market purchases.
Which hedge funds own KPTI?
7 13F filers hold KPTI among their 50 largest positions, worth $45.9M combined. The biggest bets by portfolio weight are Kalehua Capital Management LLC (4.8%), Acorn Capital Advisors, LLC (4.0%) and Catalio Capital Management, LP (1.7%). In their latest 13Fs, 2 managers opened a new position and 3 added to one.
Has Congress traded KPTI?
Members of Congress have disclosed 1 KPTI trade since 2025, 0 purchases and 1 sale in the past year; the latest was Ashley Moody (R-FL), selling $1K–15K on Feb 20, 2025.
Who is the largest holder of KPTI?
Among 13F filers, Acorn Capital Advisors, LLC reports the largest KPTI position, $14.8M (1,518,113 shares) in its Q2 2026 13F. The biggest bet by portfolio weight is Kalehua Capital Management LLC's: 4.8% of its portfolio.
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