AMLX · Insider trading · 13F holders · Congress trades
Amylyx Pharmaceuticals, Inc. (AMLX)
Who is buying and selling AMLX: company insiders on SEC Form 4, hedge funds and superinvestors on Form 13F, and members of Congress under the STOCK Act. Every figure links to the filing or page it comes from.
- 13F filers holding
- 21
- Insider buys, 90 days
- $0
- Insider sales, 90 days
- $3.8M
- Congress trades, 12 months
- 1
AMLX at a glance
- Between Aug 1, 2026 and Oct 29, 2026, 6 AMLX insiders filed 6 sales worth $3.8M on SEC Form 4, and no open-market purchases; 1 of the sales were pre-planned under Rule 10b5-1.
- 21 13F filers hold AMLX among their 50 largest positions, worth $657.0M combined, including Joseph Edelman. The biggest bets by portfolio weight are Saturn V Capital Management LP (11.9%), Commodore Capital LP (6.0%) and Almitas Capital LLC (4.2%). In their latest 13Fs, 0 managers opened a new position and 5 added to one.
- Members of Congress have disclosed 1 AMLX trade since 2022, 1 purchase and 0 sales in the past year; the latest was Chris Jacobs (R-NY), buying $1K–15K on Oct 12, 2022.
- AMLX last closed at $28.68 on Oct 29, 2026.
AMLX insider trading
Between Aug 1, 2026 and Oct 29, 2026, 6 AMLX insiders filed 6 sales worth $3.8M on SEC Form 4, and no open-market purchases; 1 of the sales were pre-planned under Rule 10b5-1.
| Filed | Insider | Role | Trade | Shares | Price | Value | Form 4 |
|---|---|---|---|---|---|---|---|
| Oct 7, 2026 | Milne George M Jr | Director | Sale10b5-1 | 30,000 | $27.70 | $831K | SEC |
| Sep 14, 2026 | Cohen Joshua B | Co-Chief Executive Officer, Director | Sale | 30,464 | $32.19 | $981K | SEC |
| Sep 14, 2026 | Klee Justin B. | Co-Chief Executive Officer, Director | Sale | 30,464 | $32.18 | $980K | SEC |
| Sep 14, 2026 | Frates James M | Chief Financial Officer | Sale | 10,810 | $32.36 | $350K | SEC |
| Sep 14, 2026 | Bedrosian Camille L | Chief Medical Officer | Sale | 10,028 | $32.40 | $325K | SEC |
| Sep 14, 2026 | Mazzariello Gina | Chief Legal Officer | Sale | 9,536 | $32.46 | $310K | SEC |
Who owns AMLX? Hedge funds and superinvestors
21 13F filers hold AMLX among their 50 largest positions, worth $657.0M combined, including Joseph Edelman. The biggest bets by portfolio weight are Saturn V Capital Management LP (11.9%), Commodore Capital LP (6.0%) and Almitas Capital LLC (4.2%). In their latest 13Fs, 0 managers opened a new position and 5 added to one.
Superinvestors holding AMLX: Joseph Edelman 2.3%
| Manager | % of portfolio | Value | Shares | Last quarter | 13F |
|---|---|---|---|---|---|
| Joseph EdelmanHedge fund | 2.3% | $149.7M | 8,334,882 | +0.6% shares | Q2 2026 |
| TCG Crossover Management, LLCHedge fund | 2.7% | $112.1M | 6,243,812 | +0.0% shares | Q2 2026 |
| Commodore Capital LPHedge fund | 6.0% | $101.5M | 5,650,000 | +0.0% shares | Q2 2026 |
| Saturn V Capital Management LPHedge fund | 11.9% | $83.0M | 4,624,101 | +6.3% shares | Q2 2026 |
| First Light Asset Management, LLCHedge fund | 3.3% | $54.3M | 3,023,256 | -5.2% shares | Q2 2026 |
| Siren, L.L.C.Investment manager | 0.5% | $26.6M | 1,480,586 | +20.4% shares | Q2 2026 |
| 683 Capital Management, LLCHedge fund | 2.2% | $23.0M | 1,279,512 | -16.4% shares | Q2 2026 |
| Almitas Capital LLCHedge fund | 4.2% | $17.5M | 974,881 | -54.1% shares | Q2 2026 |
| Jones Hill Capital LPHedge fund | 3.4% | $16.1M | 894,058 | -44.1% shares | Q2 2026 |
| Boxer Capital Management, LLCHedge fund | 1.1% | $14.4M | 800,000 | +0.0% shares | Q2 2026 |
| Great Point Partners LLCHedge fund | 3.0% | $12.6M | 700,000 | -60.0% shares | Q2 2026 |
| Parkman Healthcare Partners LLCHedge fund | 0.7% | $7.2M | 398,782 | -35.8% shares | Q2 2026 |
| HighVista Strategies LLCHedge fund | 1.6% | $6.9M | 386,080 | +9.7% shares | Q2 2026 |
| Stempoint Capital LPHedge fund | 1.2% | $6.9M | 384,304 | -42.6% shares | Q2 2026 |
| Tetragon Partners GP LtdHedge fund | 0.9% | $5.4M | 297,926 | -6.3% shares | Q2 2026 |
| Moody Aldrich Partners LLCAsset manager | 1.0% | $5.0M | 172,420 | — | Q3 2026 |
| Cormorant Asset Management, LPHedge fund | 0.2% | $3.6M | 200,000 | -42.9% shares | Q2 2026 |
| Aldebaran Capital, LLCWealth manager | 2.6% | $3.5M | 195,892 | -1.0% shares | Q2 2026 |
| Acuta Capital Partners, LLCHedge fund | 2.1% | $3.0M | 168,115 | +11.3% shares | Q2 2026 |
| Alpha Wave Global, LPHedge fund | 0.0% | $2.8M | 155,422 | +9.2% shares | Q2 2026 |
| Elmind Capital, LPHedge fund | 0.5% | $2.0M | 112,000 | +0.0% shares | Q2 2026 |
Each manager counts with its latest 13F (Q3 2026: 1, Q2 2026: 20). Screen AMLX in the grand portfolio →
AMLX stock trades by members of Congress
Members of Congress have disclosed 1 AMLX trade since 2022, 1 purchase and 0 sales in the past year; the latest was Chris Jacobs (R-NY), buying $1K–15K on Oct 12, 2022.
| Filed | Member | Trade | Amount | Traded | Since |
|---|---|---|---|---|---|
| Nov 16, 2022 | Chris JacobsR-NY · House | Buy | $1K–15K | Oct 12, 2022 | -15.9% |
Analysis mentioning AMLX
Posts from the blog that cover Amylyx Pharmaceuticals, Inc., newest first.
AMLX questions and answers
Are insiders buying AMLX stock?
Between Aug 1, 2026 and Oct 29, 2026, 6 AMLX insiders filed 6 sales worth $3.8M on SEC Form 4, and no open-market purchases; 1 of the sales were pre-planned under Rule 10b5-1.
Which hedge funds own AMLX?
21 13F filers hold AMLX among their 50 largest positions, worth $657.0M combined, including Joseph Edelman. The biggest bets by portfolio weight are Saturn V Capital Management LP (11.9%), Commodore Capital LP (6.0%) and Almitas Capital LLC (4.2%). In their latest 13Fs, 0 managers opened a new position and 5 added to one.
Has Congress traded AMLX?
Members of Congress have disclosed 1 AMLX trade since 2022, 1 purchase and 0 sales in the past year; the latest was Chris Jacobs (R-NY), buying $1K–15K on Oct 12, 2022.
Who is the largest holder of AMLX?
Among 13F filers, Joseph Edelman reports the largest AMLX position, $149.7M (8,334,882 shares) in its Q2 2026 13F. The biggest bet by portfolio weight is Saturn V Capital Management LP's: 11.9% of its portfolio.
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